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Data Driven MLB Predictions for April 16, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Reds | Finnegan | 38% | 3 | +125 | 7.5 |
| Cardinals | Wainwright | 62% | 4 | -135 | |
| Rockies | Bergman | 29% | 4 | +260 | 7 |
| Cubs | Arrieta | 71% | 5 | -320 | |
| Brewers | Jungmann | 41% | 4 | +135 | 8 |
| Pirates | Niese | 59% | 5 | -145 | |
| Nationals | Scherzer | 55% | 5 | -190 | 6.5 |
| Phillies | Nola | 45% | 4 | +170 | |
| Braves | Norris | 38% | 4 | +125 | 8.5 |
| Marlins | Koehler | 62% | 5 | -135 | |
| Diamondbacks | Miller | 53% | 5 | -108 | 7 |
| Padres | Cashner | 47% | 4 | -102 | |
| Giants | Cueto | 53% | 5 | -105 | 7.5 |
| Dodgers | Kazmir | 47% | 4 | -105 | |
| Mariners | F. Hernandez | 42% | 4 | -120 | 7.5 |
| Yankees | Sabathia | 58% | 5 | +110 | |
| Angels | Weaver | 53% | 5 | +110 | 9 |
| Twins | Nolasco | 47% | 4 | -120 | |
| Royals | Young | 42% | 4 | +132 | 7 |
| A’s | Gray | 58% | 5 | -142 | |
| Blue Jays | Estrada | 49% | 4 | +122 | 8 |
| Red Sox | Price | 51% | 5 | -132 | |
| White Sox | Danks | 41% | 4 | +133 | 8 |
| Rays | Ramirez | 59% | 5 | -143 | |
| Tigers | Verlander | 44% | 4 | +120 | 9 |
| Astros | McHugh | 56% | 5 | -130 | |
| Orioles | Gallardo | 54% | 5 | +102 | 10 |
| Angels | Lewis | 46% | 4 | -112 | |
| Mets | Harvey | 66% | 5 | -125 | 7 |
| Indians | Tomlin | 34% | 4 | +115 |
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