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Data Driven MLB Predictions for April 27, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Padres | Cashner | 44% | 4 | +153 | 7.5 |
| Giants | Samardzija | 56% | 5 | -163 | |
| Phillies | Hellickson | 33% | 4 | +180 | 7.5 |
| Nationals | Gonzalez | 67% | 5 | -200 | |
| Reds | Moscot | 19% | 3 | +199 | |
| Mets | Harvey | 81% | 5 | -215 | |
| Brewers | Jungmann | 34% | 4 | +288 | 11 |
| Cubs | Arrieta | 66% | 5 | -325 | |
| Pirates | Niese | 65% | 5 | -117 | 8.5 |
| Rockies | Gray | 35% | 4 | +107 | |
| Cardinals | Wainwright | 50% | 3 | -104 | 8.5 |
| Diamondbacks | Corbin | 50% | 4 | -106 | |
| Marlins | Nicolino | 40% | 4 | +148 | 7.5 |
| Dodgers | Kazmir | 60% | 5 | -158 | |
| White Sox | Quinatana | 30% | 4 | +118 | 8 |
| Blue Jays | Estrada | 70% | 5 | -128 | |
| A’s | Gray | 53% | 4 | -102 | 8 |
| Tigers | Verlander | 47% | 3 | -108 | |
| Orioles | Tillman | 46% | 4 | +106 | 7.5 |
| Rays | Moore | 54% | 5 | -116 | |
| Yankees | Sabathia | 52% | 4 | -101 | 9 |
| Rangers | Perez | 48% | 3 | -109 | |
| Indians | Tomlin | 44% | 4 | -111 | 8.5 |
| Twins | Berrios | 56% | 5 | +101 | |
| Royals | Young | 50% | 5 | +101 | 7.5 |
| Angels | Tropeano | 50% | 4 | -111 | |
| Astros | McHugh | 43% | 4 | +120 | 7.5 |
| Mariners | Iwakuma | 57% | 5 | -130 | |
| Braves | Norris | 24% | 4 | +170 | 8.5 |
| Red Sox | Wright | 76% | 5 | -180 |
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