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Data Driven MLB Predictions for June 21, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Giants | Cueto | 62% | 4 | -172 | 8 |
| Pirates | Boscan | 38% | 3 | +162 | |
| Braves | Norris | 36% | 3 | +268 | 7 |
| Marlins | Fernandez | 64% | 5 | -300 | |
| Cardinals | Wainwright | 35% | 3 | +137 | |
| Cubs | Hammel | 65% | 5 | -147 | |
| Nationals | Roark | 56% | 4 | +106 | 7.5 |
| Dodgers | Kazmir | 44% | 3 | -116 | |
| Mariners | Paxton | 53% | 5 | +125 | 9 |
| Tigers | Verlander | 47% | 4 | -135 | |
| White Sox | Sale | 60% | 5 | -102 | 9 |
| Red Sox | Buchholz | 40% | 4 | -108 | |
| Rays | Snell | 47% | 4 | +161 | 8 |
| Indians | Kluber | 53% | 5 | -171 | |
| Angels | Santiago | 47% | 4 | +138 | 8.5 |
| Astros | McHugh | 53% | 5 | -148 | |
| Rockies | Bettis | 46% | 4 | +148 | 9 |
| Yankees | Nova | 54% | 5 | -158 | |
| Padres | Perdomo | 47% | 4 | +168 | 9.5 |
| Orioles | Wilson | 53% | 5 | -178 | |
| Diamondbacks | Corbin | 37% | 3 | +151 | 9 |
| Blue Jays | Estrada | 63% | 5 | -161 | |
| Royals | Kennedy | 35% | 2 | +171 | 7 |
| Mets | Syndergaard | 65% | 4 | -181 | |
| Reds | DeSclafani | 40% | 3 | +178 | 9.5 |
| Rangers | Lewis | 60% | 5 | -188 | |
| Phillies | Nola | 58% | 5 | -107 | 8.5 |
| Twins | Duffey | 42% | 4 | -103 | |
| Brewers | Nelson | 55% | 5 | +125 | 8 |
| A’s | Gray | 45% | 4 | -135 |
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