Data Driven MLB Predictions for May 16, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Braves | Perez | 46% | 4 | +165 | 8 |
| Pirates | Niese | 54% | 5 | -175 | |
| Marlins | Conley | 52% | 5 | -105 | 7.5 |
| Phillies | Eickhoff | 48% | 4 | -105 | |
| Red Sox | Porcello | 55% | 5 | -107 | 8 |
| Royals | Ventura | 45% | 3 | -103 | |
| Rays | Smyly | 46% | 3 | +115 | 8 |
| Blue Jays | Happ | 54% | 4 | -125 | |
| Twins | Berrios | 41% | 3 | +150 | 8.5 |
| Tigers | Zimmermann | 59% | 5 | -160 | |
| Rangers | Holland | 49% | 4 | -107 | 8 |
| A’s | Manaea | 51% | 5 | -103 | |
| Reds | Lamb | 50% | 5 | +143 | 8.5 |
| Indians | Anderson | 50% | 4 | -153 | |
| Yankees | Pineda | 45% | 4 | +101 | 9 |
| Diamondbacks | Ray | 55% | 5 | -111 | |
| Angels | Shoemakers | 37% | 3 | +173 | 7.5 |
| Dodgers | Maeda | 63% | 6 | -183 |
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