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Data Driven MLB Predictions for May 23, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Mets | Colon | 46% | 3 | +138 | 7.5 |
| Nationals | Gonzalez | 54% | 4 | -148 | |
| Cubs | Lackey | 55% | 6 | -118 | 7 |
| Cardinals | Wainwright | 45% | 4 | +108 | |
| Reds | Finnegan | 44% | 3 | +315 | 6.5 |
| Dodgers | Kershaw | 56% | 5 | -360 | |
| Padres | Pomeranz | 49% | 3 | +170 | 6.5 |
| Giants | Cueto | 51% | 4 | -180 | |
| Angels | Tropeano | 51% | 4 | +108 | 9.5 |
| Rangers | Hollan | 49% | 3 | -118 | |
| Indians | Anderson | 43% | 4 | +107 | 9 |
| White Sox (Game 2) | Johnson | 57% | 6 | -117 | |
| Royals | Kennedy | 52% | 4 | -133 | 8.5 |
| Twins | Nolasco | 48% | 3 | +123 | |
| A’s | Hill | 48% | 3 | +114 | 7 |
| Mariners | Walker | 52% | 4 | -124 | |
| Phillies | Velasquez | 52% | 4 | +101 | 8.5 |
| Tigers | Pelfrey | 48% | 3 | -111 | |
| Rays | Moore | 47% | 4 | +107 | 7.5 |
| Marlins | Chen | 53% | 5 | -117 | |
| Indians | Clevinger | 48% | 3 | +120 | 9 |
| White Sox (Game 1) | Latos | 52% | 4 | -130 |
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