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Data Driven MLB Predictions for May 25, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Mets | Matz | 49% | 3 | -105 | 7.5 |
| Nationals | Roark | 51% | 4 | -105 | |
| Cubs | Arrieta | 54% | 5 | -170 | 7 |
| Cardinals | Martinez | 46% | 4 | +155 | |
| Padres | Shields | 55% | 5 | +139 | 7.5 |
| Giants | Peavy | 45% | 4 | -149 | |
| Diamondbacks | De La Rosa | 51% | 5 | +115 | 8.5 |
| Pirates | Locke | 49% | 4 | -125 | |
| Brewers | Guerra | 53% | 5 | -113 | 7.5 |
| Braves | Foltynewicz | 47% | 4 | +103 | |
| Reds | Straily | 52% | 5 | +150 | 7.5 |
| Dodgers | Kazmir | 48% | 4 | -160 | |
| Royals | Gee | 49% | 3 | -109 | 8.5 |
| Twins | Duffey | 51% | 4 | -101 | |
| Angels | Santiago | 46% | 3 | +115 | 9.5 |
| Rangers | Lewis | 54% | 4 | -125 | |
| Indians | Kluber | 45% | 3 | +100 | 7.5 |
| White Sox | Quintana | 55% | 4 | -110 | |
| Blue Jays | Estrada | 53% | 4 | +100 | 9 |
| Yankees | Nova | 47% | 3 | -110 | |
| Orioles | Wilson | 53% | 5 | +123 | 8.5 |
| Astros | McHugh | 47% | 4 | -133 | |
| A’s | Zeal | 47% | 4 | +155 | 7.5 |
| Mariners | Iwakuma | 53% | 5 | -170 | |
| Phillies | Nola | 53% | 4 | +112 | 8.5 |
| Tigers | Sanchez | 47% | 3 | -122 | |
| Rockies | Bettis | 45% | 4 | +165 | 9.5 |
| Red Sox | Wright | 55% | 5 | -175 | |
| Marlins | Nicolino | 49% | 3 | +150 | 8.5 |
| Rays | Andriese | 51% | 4 | -165 |
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