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Data Driven MLB Predictions for May 4, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Giants | Peavy | 46% | 5 | -131 | 9 |
| Reds | Straily | 54% | 6 | +121 | |
| Cubs | Lester | 54% | 5 | -136 | 7.5 |
| Pirates | Nicasio | 46% | 4 | +126 | |
| Braves | Chacin | 43% | 3 | +182 | 7 |
| Mets | Matz | 57% | 5 | -192 | |
| Rockies | Chatwood | 55% | 5 | -103 | 7.5 |
| Padres | Vargas | 45% | 4 | -107 | |
| Diamondbacks | De La Rosa | 49% | 4 | +160 | 7.5 |
| Marlins | Fernandez | 51% | 5 | -170 | |
| Phillies | Morgan | 46% | 4 | +150 | 7.5 |
| Cardinals | Leake | 54% | 5 | -160 | |
| Mariners | Hernandez | 56% | 4 | -137 | 7 |
| A’s | Manaea | 44% | 3 | +127 | |
| Tigers | Sanchez | 47% | 4 | +143 | 7.5 |
| Indians | Kluber | 53% | 5 | -153 | |
| Yankees | Sabathia | 45% | 3 | +114 | 8.5 |
| Orioles | Wilson | 55% | 4 | -124 | |
| Rangers | Lewis | 49% | 3 | +157 | 8.5 |
| Blue Jays | Sanchez | 51% | 4 | -167 | |
| Twins | Hughes | 49% | 4 | +115 | 8 |
| Astros | Fiers | 51% | 5 | -125 | |
| Red Sox | Buchholz | 48% | 4 | -112 | 8.5 |
| White Sox | Danks | 52% | 5 | +102 | |
| Angels | Santaigo | 52% | 4 | -133 | 9 |
| Brewers | Davies | 48% | 3 | +123 | |
| Nationals | Strasburg | 52% | 4 | -132 | 7.5 |
| Royals | Medlen | 48% | 3 | +122 | |
| Dodgers | Wood | 47% | 3 | +134 | 7.5 |
| Rays | Smyly | 53% | 4 | -145 |
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