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Data Driven MLB Predictions for May 5, 2016:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Phillies | Eickhoff | 43% | 4 | +165 | 7.5 |
| Cardinals | Garcia | 57% | 5 | -175 | |
| Diamondbacks | Ray | 48% | 4 | +113 | 8 |
| Marlins | Conley | 52% | 5 | -123 | |
| Brewers | Anderson | 48% | 4 | +102 | 8.5 |
| Reds | Simon | 52% | 5 | -112 | |
| Nationals | Ross | 46% | 4 | +130 | |
| Cubs | Hendricks | 54% | 5 | -140 | |
| Mets | deGrom | 55% | 5 | -170 | 7 |
| Padres | Rea | 45% | 3 | +160 | |
| Rockies | Rusin | 53% | 6 | +130 | 8 |
| Giants | Cain | 47% | 5 | -140 | |
| Tigers | Fulmer | 50% | 5 | +125 | 8.5 |
| Indians | Bauer | 50% | 4 | -135 | |
| Yankees | Tanaka | 48% | 3 | +100 | 8 |
| Orioles | Gausman | 52% | 4 | -110 | |
| Rangers | Holland | 51% | 4 | +150 | 8.5 |
| Blue Jays | Happ | 49% | 3 | -160 | |
| Mariners | Miley | 50% | 5 | -110 | 8.5 |
| Astros | Devenski | 50% | 4 | +100 | |
| Red Sox | Owens | 51% | 5 | -115 | 8.5 |
| White Sox | Johnson | 49% | 4 | +105 |
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