Get our data driven MLB predictions for all of tonight’s games including Cardinals at Pirates, Nationals at Mets, Phillies at Braves, Cubs at Brewers, Marlins at Diamondbacks, Rockies at Padres, Giants at Dodgers, Rays at Orioles, Yankees at Blue Jays, Twins at Tigers, Angels at Astros, Royals at White Sox, Rangers at A’s, Indians at Mariners and Red Sox at Reds.
MLB Predictions for September 22, 2017:
| TEAM | PITCHER | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Cardinals | Wacha | 63% | 5 | -153 | 8.5 |
| Pirates | Nova | 37% | 4 | +138 | |
| Nationals | E. Jackson | 51% | 5 | +130 | 8.5 |
| Mets | deGrom | 49% | 4 | -140 | |
| Phillies | Lively | 50% | 5 | +110 | 9.5 |
| Braves | Newcomb | 50% | 4 | -121 | |
| Cubs | Lackey | 40% | 4 | -125 | 9 |
| Brewers | Woodruff | 60% | 5 | +!15 | |
| Marlins | Conley | 15% | 4 | +218 | 9 |
| Diamondbacks | Greinke | 85% | 5 | -245 | |
| Rockies | J. Gray | 91% | 5 | -160 | 8.5 |
| Padres | Lyles | 9% | 4 | +150 | |
| Giants | Samardzija | 26% | 4 | +203 | 7.5 |
| Dodgers | Hill | 74% | 5 | -220 | |
| Rays | Cobb | 76% | 5 | -105 | 9.5 |
| Orioles | Hellickson | 24% | 4 | -105 | |
| Yankees | Tanaka | 66% | 5 | -159 | 9 |
| Blue Jays | Estrada | 34% | 4 | +149 | |
| Twins | Gibson | 50% | 6 | ||
| Tigers | Norris | 50% | 5 | ||
| Angels | Richards | 40% | 4 | +153 | 8 |
| Astros | Verlander | 60% | 5 | -170 | |
| Royals | Hammel | 47% | 4 | -125 | 9.5 |
| White Sox | R. Lopez | 53% | 5 | +115 | |
| Rangers | N. Martinez | 31% | 5 | +117 | 9.5 |
| A’s | Graveman | 69% | 6 | -127 | |
| Indians | Bauer | 59% | 5 | -170 | 8.5 |
| Mariners | E. Ramirez | 41% | 4 | +160 | |
| Red Sox | Porcello | 47% | 4 | -135 | 9.5 |
| Reds | Romano | 53% | 5 | +125 |
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