Week 16 is an eliminator for several teams trying to make the playoffs. We see some games being lopsided as there appear to be some mismatches this week. Here’s how NFL Week 16 plays out:
| TEAM | SCORE | VEGAS LINE |
| Falcons | 28 | -3.5 |
| Lions | 24 | 50.5 |
| Titans | 13 | 12.5 |
| Packers | 37 | 46 |
| Raiders | 17 | 8.5 |
| Panthers | 27 | 46 |
| Bills | 17 | 4.5 |
| Dolphins | 24 | 41.5 |
| Bengals | 17 | 3.5 |
| Steelers | 24 | 42 |
| Patriots | 37 | -14.5 |
| Jaguars | 14 | 50 |
| Colts | 24 | -7 |
| Chiefs | 20 | 41.5 |
| Saints | 28 | 3 |
| Cowboys | 27 | 51.5 |
| Redskins | 27 | -6.5 |
| Eagles | 20 | 45 |
| Rams | 16 | 3 |
| Buccaneers | 24 | 43.5 |
| Giants | 23 | -2.5 |
| Ravens | 24 | 47.5 |
| Vikings | 16 | 7.5 |
| Texans | 28 | 45 |
| Browns | 14 | 13 |
| Broncos | 30 | 44.5 |
| Bears | 24 | -5.5 |
| Cardinals | 13 | 36.5 |
| 49ers | 21 | -1 |
| Seahawks | 20 | 39 |
| Chargers | 21 | 2.5 |
| Jets | 20 | 39 |