Data Driven MLB Predictions for September 22, 2015:
| TEAM | WIN % | SCORE | VEGAS LINE | RUN TOTAL |
| Braves | 38% | 4 | +201 | 8 |
| Mets | 62% | 5 | -218 | |
| Phillies | 43% | 4 | +152 | 8 |
| Marlins | 57% | 5 | -162 | |
| Brewers | 28% | 3 | ||
| Cubs | 72% | 5 | ||
| Reds | 28% | 4 | +194 | 8 |
| Cardinals | 72% | 5 | -210 | |
| Pirates | 67% | 5 | -134 | 11 |
| Rockies | 33% | 3 | +124 | |
| Diamondbacks | 50% | 5 | +157 | 7 1/2 |
| Dodgers | 50% | 4 | -167 | |
| Giants | 50% | 5 | +108 | 7 |
| Padres | 50% | 4 | -118 | |
| Yankees | 46% | 4 | +132 | 8 1/2 |
| Blue Jays | 54% | 5 | -142 | |
| White Sox | 53% | 4 | -117 | 9 |
| Tigers | 47% | 3 | +107 | |
| Rays | 33% | 4 | +127 | 9 |
| Red Sox | 67% | 5 | -137 | |
| Indians | 54% | 5 | -121 | 8 |
| Twins | 46% | 4 | +111 | |
| Angels | 46% | 3 | +159 | 8 1/2 |
| Astros | 54% | 4 | -169 | |
| Mariners | 54% | 5 | -108 | 8 |
| Royals | 46% | 4 | -102 | |
| Rangers | 43% | 4 | -125 | 8 |
| A’s | 57% | 5 | +115 | |
| Orioles | 47% | 4 | +118 | 8 |
| Nationals | 53% | 5 | -128 |
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